Epithelioid mesothelioma : The most common cell type for cancer

Epithelioid Mesothelioma

Epithelioid mesothelioma : The most common cell type for cancer

It is noted in a research that most mesothelioma patients have epithelioid cell type. Epithelioid mesothelioma is detected in 70% of the cases. Mesothelioma life expectancy is quite high as it is the most curable subtype.

What exactly is epithelioid mesothelioma ?

The healthy epithelial cells has the capability of turning into deadly epithelioid mesothelioma if exposed to asbestos. Mesothelioma life expectancy is high as the prognosis is better and treatment options are more than sarcomatoid or biphasic cell types.

Characteristics of Epithelioid Mesothelioma

Cell prevalence

The prognosis and diagnosis of epithelioid mesothelioma is most common. 75% of the epithelioid cases are reported in peritoneal mesothelioma patients. But 60% of the diagnosis takes place in pleural mesothelioma patients.

Cell description

Epithelioid cells are easily recognisable as they have a defined, elongated egg shape. The prominent nuclei makes the cells distinguishable from other cell types.

Cell behaviour

Epithelioid cells are the faster dividing cells than other mesothelioma cell types. This leads to increasing tumor growth. Although the cells remain stuck to each other, resulting in slow metastasis.

Treatment

The treatment of epithelioid mesothelioma is not different from other types of mesothelioma. In fact the treatment of this is more effective than the other types.

Some patients are treated with extrapleural pneumonectomy (EPP), which has the highest probability of mesothelioma life expectancy. For patients in whom the tumor hasn’t spread yet from pluera to the lung, lung-sparing pleurectomy with decortication (P/D)  can be effective.

The ones suffering from epithelioid peritoneal mesothelioma can go through cytoreductive surgery. The other common standard forms such as chemotherapy and radiation are some alternative options.

Subtypes of Epithelioid Mesothelioma.

Adenoid. This type of cells are present in almost every type of mesothelioma. These cells commonly develop in genital tract. But pleural adenocarcinoma is a very rare case to be reported. The symptoms are so similar to other types of diseases that it becomes difficult to diagnose Adenoid. Adenoid mesothelioma is common in men.

Small cell. The shape of the cell makes the small cell mesothelioma distinct in pattern. This kind of cells account for less than 6% of the mesotheliomas. It generally forms in the lining of the peritoneum and pleura. It is very rarely seen in the pericardium. Small cell mesothelioma is often misdiagnosed as small cell lung cancer.

Cystic. Cystic mesothelioma cells are very rare and non cancerous. These cells generally develop in the peritoneal or pleural cavity. Asbestos is not the reason for cystic mesothelioma.

Papillary. Papillary mesothelioma is also non-cancerous and non-asbestos related. This is common in women. The cells often grow in the lining of abdomen and lung. It can be created just as malignant mesothelioma, but the normal characteristics of mesothelioma do not match.

Also Read :

Recommended articles